When Penny, a pretty woman and an aspiring actress from Omaha, moves into the apartment across the hall from Leonard and Sheldon's, Leonard has another aspiration in life, namely to get Penny to be his girlfriend.
Despite the fact that some viewers take Sheldon's behavior, mannerisms, and social skills as a sign that Sheldon has Asperger's syndrome or otherwise falls on the autism spectrum, the show-runners have persistently denied in many interviews that Sheldon has Asperger's or any other type of autism.
They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways.
They are also friends with their Cal Tech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali.
The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books.
As they are self-professed nerds, all have little or no luck with women.
They decide to have everyone over for one last Mrs. The same pale yellow refrigerator now is hinged on the left side so that the camera can film the inside of the freezer, filled with Brisket, Kugal, Meatloaf, and Chicken soup.
Late that same season, (823) Howard, Raj, and Stewart are cleaning the kitchen ("It's A Hard Knock Life" Charnin/ Strouse) and the hinges are back on the right.
It should be noted however, that actor Jim Parsons (Sheldon) has stated that he does think that Sheldon actually does have Asperger's syndrome and portrays him as such. ") and the refrigerator doors open with hinges on the RIGHT so the camera can't film it's contents.See more » In Season 7, (708) everyone has Thanksgiving at the Wollowitz home (Penny learns she's married to Zach.) Raj is in the kitchen cooking as Mrs. In Season 8, (818) a power failure causes all of Howard's late mother's cooking to thaw, creating a strong emotional reaction from Howard.